Ion Release and Antibacterial Activity of Calcium- Fluoride ‎Releasing Self-Adhesive Resin Cement and Conventional Self-‎Adhesive Resin Cement: An In-Vitro Study

Document Type : Original articles

Authors

1 Demonstrator of Dental Materials, Biomaterials department, Faculty of Dentistry, Sphinx University, Assiut, Egypt.

2 dental material department,faculty of dentistry, Minia university

3 Biomaterials Department Faculty of Dentistry Minia University

10.21608/asdj.2025.346546.1750

Abstract

Aim: To investigate the ion release and antibacterial activity of calcium-fluoride releasing self-adhesive resin cement and conventional self-adhesive resin cement.
Materials and methods: Forty specimens were prepared and divided into two groups according to the cement type: (Group I) calcium-fluoride releasing self-adhesive resin cement (TheraCem®) and (Group II) conventional self-adhesive resin cement (Nova Resin). Each group was separated into 2 subgroups; According to the type of test that were performed: subgroup for ion release assessment of fluoride, calcium and phosphorus (n= 10) and subgroup for Antibacterial assessment against Streptococcus Mutans (n= 10). A direct contact test was carried out to assess bacterial growth. Calcium and phosphorus ions were analyzed using inductively coupled plasma mass spectrometry (ICP-MS) whereas fluoride ions release was analyzed by ion chromatography (I C). Data was collected and IBM SPSS Statistics for Windows, Version 23.0 used for analysis. using the student’s t-test, Two-Way ANOVA test and Spearman’s correlation coefficient. The significance level was set at P ≤ 0.05.
Results: For ion release test, Group I showed statistically significant higher mean F, Ca and P ion release than Group II (P <0.001). For antibacterial activity test, Group II exhibited a statistically significant difference in mean bacterial count when compared to Group I. (P <0.001).
Conclusion: calcium- fluoride releasing self-adhesive resin cement (TheraCem®) has more antibacterial properties than conventional self-adhesive resin cement (Nova Resin) since it releases calcium, phosphorus and fluoride ions.

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