Clinical and Histological Evaluation of Gingival Tissues in Different Stages of Periodontitis

Document Type : Original articles

Authors

1 Lecturer of oral and dental medicine department, Faculty of dental medicine for girls, Al Azhar University

2 Lecturer of Oral and Dental Biology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt

3 Associate Professor of Oral and Dental Biology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt

10.21608/asdj.2025.347964.1755

Abstract

Aim: The objective of the present study was to assess the structure of gingival tissues during various phases of periodontitis and the following were drawn: clinically and histologically
Materials and Methods: In this study thirty-six adult male albino rats weighing between 220-250 grams were employed. The rats were separated into four groups: the control group, which included six rats, group II included ten rats, Group III included ten rats and Group IV included ten rats. Thirty-six male and female patients were chosen among those who visited the department of oral medicine and periodontology’s outpatient clinic at al Azhar University’s faculty of dental medicine to participate in this study. Patient’s ages were between 30 and 60 years. Before beginning any operation, all subjects were getting the information regarding the purpose of the study as well as its advantages. All patients were asked to sign a written consent form indicating that they had been fully informed about the planned research program and experimental design. The samples were prepared for statistical and histological examination
 Results: Periodontitis affected gingival health and made Spacing of epithelial cell layers, vacillation of lamina propria, numerous of hyperemic vessels exist in an infiltrated connective tissue. The increasing in inflammatory cells and extravasation of blood vessels were observed.
 Conclusion: The gingival health tissue and the severity of periodontitis were directly correlated. In case of the increasing of the gingival inflammatory processes led to the increasing of angiogenesis and inflammatory cell infiltration in the connective tissue and vice versa.

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