Evaluation of the Effectuality of Using Sticky Bone Combined ‎with Platelet Rich Fibrin Membrane in the Management of ‎Intrabony Defects: A Randomized Controlled Clinical Trial

Aim: In this randomized controlled clinical trial, sticky bone combined with PRF membrane (SB –PRF) was used and compared to collagen membrane and bone graft (CM-BG) using the same graft material to determine its regenerative efficacy& capacity.
Materials and Methods: According to our study, A total of (24) IBDs were treated by (SB –PRF) representing test group and (CM-BG) representing the control one. Periodontal regenerative evaluation was both clinically and radiographically performed. The clinical parameters including probing pocket depth (PPD) and clinical attachment level (CAL), Gingival index (GI) and plaque index (PI) were assessed at baseline and 6 months postoperatively, whereas radiographic assessment was exerted by a direct digital image radiographic system to obtain and calculate bone changes using the image processing software at baseline and 6 months
Results Both the study treatment groups (SB –PRF) & (CM-BG) showed statistically significant improvements clinically and radiographically at 6 months in terms of PI, GI, PPD, CAL, defect fill measurement compared to baseline. However, there were insignificant difference in terms of both the clinical and radiographic parameters after 6 months between the two groups.
Conclusion: Intra-bony defects treated with sticky bone combined with PRF membrane showed improved clinical and radiographic parameters that are demonstrative of the enhanced periodontal regenerative efficacy compared to the use of bone grafting material conjugated with collagen membrane.